Research Activities:Biosensor Development Development of enzymatic and antibody based biosensors for clinical / environmental applications Synthesis of nanoparticles (inorganic, polymer and semiconductor) for immunodiagnosis and therapeutic applications. Design and development of antibody based immunobiosensors for monitoring various organic/inorganic/biomolecular substances. Expertise and Synergistic Activities: Generation of specific antibodies (IgG and IgY types) and aptamers against toxins (pesticides, aflatoxin etc), narcotic drugs (heroin, morphine, cocaine etc.) and surface antigens (outer membrane protein, biomarkers etc) for clinical diagnosis. Optimization of biomolecular immobilization techniques for a stable coupling of the antibodies to the transducer surface without comprising their biological activity. Characterization of the bio-interface upto the molecular resolution by different physical techniques, such as Scanning Electron Microscope (SEM), Scanning Tunneling Microscope (STM), Atomic Force Microscopes (AFM), Ellipsometer etc.. Development and standardization of immunobiosensors systems (Optical, Microgravimetric, Micromechanical, Microfluidic and Dipstick) Stability analysis of immobilized enzyme/antibody for biosensor probes and Synthesis of nanoparticles (inorganic, semicoductor and polymer based ) for immunodiagnosis and therapeutic applications. Visiting Professorship/Scientist: North-Western University, Illinois, USA EPFL, Lausanne, Switzerland NTU, Singapore Fellow: Institute of Hospital Engineering, India. DAAD, Germany Member Editorial Board: Member-Editorial Board, J. Food, Agri. and Environment, Helsink, Finland. Member-Editorial Board, Research Journal of Chem. and Environment. Member-Editorial Board, Panjab University Research Journal of Science, Chandigarh, India. Membership: Nodal officer (Chairman): Biomarker/Biosensor group, Department of Biotechnology (Govt. of India) Member- Task Force (Expert Advisory Committee) (1) Conducting Polymer and Biosensors DST India (2) Bioengineering, DBT India and (3) Low cost sensors, ICMR, India Joint Secretary, Biosensor Society of India. Life Member, Biosensor Society of India Life Member of Biophysical Society of India. Member-selection committees, IIT, CSIR and Panjabi University. Teaching Experience: Teaching M.Tech students of Panjab University, Chandigarh and PhD students (JNU, Delhi) at IMTECH Chandigarh for fulfilling their partial requirement to obtain M.Tech and PhD degrees respectively. Selected list of Publications and Patents: Recent publications (Last 5 years) Yogesh Nangia, Nishima Wangoo, Saurabh Sharma, Jin-Song Wu, Vinayak Dravid, G S Shekhawat, and C Raman Suri* (2009) Facile biosynthesis of phosphate capped gold nanoparticles by a bacterial isolate Stenotrophomonas maltophilia Appl. Phys. Lett. 94, 233901. I. Putu Mahendra Wijaya, Sonu Gandhi, Tey Ju Nie, Nishima Wangoo, Isabel Rodriguez, G. Shekhawat, C. Raman Suri*, and Subodh G. Mhaisalkar* (2009) Protein/carbon nanotubes interaction: The effect of carboxylic groups on conformational and conductance changes. Appl. Phy. Letter, 95, 073704 Fazlurrahman*, M. Batra*, J. Pandey, C.R. Suri and R.K. Jain (2009) Isolation and characterization of an atrazine-degrading Rhodococcus sp. strain MB-P1 from contaminated soil. Letters in Applied Microbiology. 49 721–729 Sonu Gandhi, Neena Caplashb, Prince Sharma, C. Raman Suri* (2009). Strip-based immunochromatographic assay using specific egg yolk antibodies for rapid detection of morphine in urine samples. Biosensors and Bioelectronics. 25, 502–505. Robin C. Boro, K. Vikas Singh and C. Raman Suri* (2009). Characterization of Hapten-Protein Conjugates: Antibody Generation and Immunoassay Development for Chlorophenoxyacetic Acid Pesticides J. AOAC Int. 92(6), 1773 . I Putu Mahendra Wijaya, Tey Ju Nie, Sonu Gandhi, Robin Boro, Alagappan Palaniappan, Goh Wei Hau, Isabel Rodriguez , C. Raman Suri, Subodh G. Mhaisalkar (2010). Femto Molar Detection of 2, 4-dichlorophenoxyacetic acid Herbicides via Competitive Immunoassays in a Microfluidic Based Carbon Nanotube Liquid Gated Transistor. Lab on Chip 10, 634-638. K. Vikas Singh, Pooja Khanna, C. Raman Suri*, and Mohan L. Garg* (2010) Structural and Immunogenic Effects of Multiple Hapten Loading on Carrier Protein. J AOAC Int 93 (1) 59. Raghuraj S. Chouhan, Kumar Vikash S. Rana, Raman C. Suri, Ravindranathan K. Thampi, and Munna S. Thakur (2010) Trace-Level Detection of Atrazine Using Immuno-chemiluminescence: Dipstick and Automated Flow Injection Analyses Formats. J AOAC Int. 93 (1) 28. Sanjay Rawat, C. Raman Suri Debendra K. Sahoo (2010) Molecular mechanism of polyethylene glycol mediated stabilization of protein. BBRC 392, 561-566. J. N. Tey, S. Gandhi, I. P. M. Wijaya, Al. Palaniappan, J. Wei, I. Rodriguez, C. Raman Suri and S. G. Mhaisalkar (2010). Direct Detection of Heroin Metabolites using a Carbon Nanotubes Liquid Gated Field Effect Transistor based Competitive Immunoassay".SMALL (Accepted; available online) Priyanka Sharma, Adity Chopra, Swaranjit Singh and C Raman Suri (2010) Efficient biotransformation of herbicide diuron by bacterial strain Micrococcus sp. PS-1. Biodegradation Journal 21, 979-987.. Nishima wangoo, Jyotsna Kaushal, K K Bhasin and C Raman Suri (2010) Zeta potential based colorimetric immunoassay for the direct detection of diabetic marker HbA1c using gold nanoprobes Chem. Comm., 46, 5755 - 5757. Priyanka Sharma, Sonu Gandhi, Adity Chopra, N. Sekar and C Raman Suri (2010) Fluoroimmunoassay based on suppression of fluorescence self-quenching for ultra-sensitive detection of herbicide diuron Anal. Chimica Acta 676, 87-92 Priyanka Sharma and C Raman Suri (2011) Biotransformation and biomonitoring of phenylurea herbicide diuron. Bioresource Technology 102, 3119–3125. Sok Yee Yew,Gajendra Shekhawa, Nishima Wangoo,Subodh Mhaisalkar, C. Raman Suri, Vinayak P Dravid and Yeng Ming Lam (2011) Design of single peptides for self-assembled conduction channels. Nanotechnology (Accepted for publication) Robin Boro, Jyotsna Kaushal, Yogesh Nangiar, Nishima Wangoo and C Raman Suri (2011) Gold nanoparticles catalyzed chemiluminescence immunoassay for detection of herbicide 2,4-dichlorophenoxyacetic acid. Analyst 136, 2125 Priyanka Sharma, Kavita Sablok, Vijendra Bhalla, and C raman Suri (2011). A novel disposable electrochemical immunosensor for phenyl urea herbicide Diuron. Biosensors and Bioelectronics, 26, 4209–4212 S. Thakur, Sonu Gandhi, A. K. Paul, C. Raman Suri (2011). A Flow Injection Immunosensor for the Detection of Atrazine in Water Samples. Sensors & Transducers Journal, 131, 91-100 Arun Chauhan, S. Zubiar, S. Tuhail, A Sherwani, C. R. Suri, A Azam and M. Owais (2011). Fungus mediated biological synthesis of gold nanoparticles: Poteintial in detection of lever cancer. International Journal of Nanomedicine 2011:6 1–15. V Bhalla, Sandro Carrara, Priyanka Sharma, Yogesh Nangia, C. Raman Suri (2012) Gold nanoparticles mediated label-free capacitance detection of cardiac Troponin. Sensors and Actuators B 161, 761-768  Book/Chapters: 1. Immunosensors for pesticides monitoring. Advances in Biosensors (Elsevier publication). Eds. APF Turner and BD Malhotra Vol. 5, pp 161-178. 2. Immunosensor for Pesticide Analysis. Nature News India (Macmillan Press) Patents: 1. Microporous filtration based dot immunoassay device for method of screening of analytes and method of use. Chander Raman Suri, Grish Chandra Varshney and Manoj Raje (US Patent No. US 7,419,640). 2. An efficient and improved method for screening of organic molecules by microporous filtration based dot immunoassay kit. Chander Raman Suri, Grish Chandra Varshney and Manoj Raje (EP Patent No. 159211 B1 3. An efficient and improved method for screening of organic molecules by microporous filtration based dot immunoassay kit. Chander Raman Suri, Grish Chandra Varshney and Manoj Raje (AU Patent No. 2002348763 B2) . 4. C.R.Suri, Jasdeep Kaur, et al . An immunoconjugate and process for preparation thereof. European Patent No. EP 1915616 B1). 5. A process for the attachment of hapten to polystyrene for immuno-affinity applications Inventors: Chander Raman Suri, Jasdeep Kaur, Kanwar Vikas Singh, Grish Chandra Varshney and Manoj Raje . Ref. No. 0049/NF/2003. 6. C.R.Suri, Jasdeep Kaur, et al . A dipstic based immunoassay for pesticide monitoring. Application file no. 1983DEL2005

Biosensor Development