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Yasuko Rikihisa

Professor
Department of Veterinary Biosciences
Food Animal Health Research Program, OARDC
United States of America

Professor Microbiology
Biography

Yasuko Rikihisa had done her PhD, MS from University of Tokyo and Postdoctoral Fellow from Harvard Medical School. At present she is Professor at The Ohio State University.

Research Intrest

Understanding the molecular pathogenic mechanisms of ehrlichiosis/anaplasmosis, vector-borne emerging infectious diseases of man (zoonosis) and animals.  Elucidation of Ligand and Receptor, and Invasion Mechanisms of Intracellular Bacteria. Determination of Nutritional Virulence of Intracellular Bacteria-Hijacking Autophagy Pathway by Bacterial Molecules Secreted by Type IV Secretion System. Analysis of Regulation of Intracellular Growth and Development by Bacterial Two-component Regulatory System. Investigation of Ehrlichia strain-variable Disease Pathogenesis In vivo Virulence Linked to Comparative Genome Sequence and Transcriptome Analysis Analysis of Molecular Mechanisms of Vector (tick, trematode) transmission, and determination of Natural Reservoirs.

List of Publications
Greiman, S., Y. Rikihisa, J. Cain, J. Vaughan, and V. Tkach (2016) Germs within worms: Localization of Neorickettsia sp. within life cycle stages of digenean Plagiorchis elegans. Appl. Environ. Microbiol. 82: 2356-2362.
Lin, M., H. Liu, Q. Xiong, H. Niu, Z. Cheng, A. Yamamoto, and Y. Rikihisa (2016) Ehrlichia secretes Etf-1 to induce autophagy and capture nutrients for its growth through RAB5 and class III phosphatidylinositol 3-kinase. Autophagy. 12: 1-22.
Lai, T-H, M.E. Parraga, E. Alvarez, and Y. Rikihisa. (2016) Anaplasma platys Immunoblot Test Using Major Surface Antigens. Vector-Borne and Zoonotic Diseases. 16: 581-587.
Xiong, Q., H. Bekebrede, P. Sharma, L. G. Arroyo, J. D. Baird, and Y. Rikihisa. (2016) An ecotype of Neorickettsia risticii causing Potomac Horse Fever in Canada. Appl. Environ. Microbiol. 82: 6030-6036.
Kumar, N., M. Lin, X. Zhao, S. Ott, I. Santana-Cruz, S. Daugherty, Y. Rikihisa, L. Sadzewicz, L. J. Tallon, C. M. Fraser, and J. C. Dunning Hotopp. (2016) Efficient Enrichment of Bacterial mRNA from Host-Bacteria Total RNA Samples. Scientific Reports, 5: 34850.
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