Valérie joined Selexis in 2010. Currently, she is head of Cell Culture, where she addresses specific secretion bottlenecks of difficult-to-express recombinant proteins. Valérie received her PhD from the University of Aix-Marseille II, where she focused on hTPO maturation and the role of ER chaperones in the folding/degradation machineries of this difficult-to-express glycoprotein. After completing her PhD, Valérie held a postdoctoral position at the UniversitätsSpital Zürich (Cell and Molecular Pathology Department) where she described a selective autophagy-mediated mechanism of misfolded and aggregated proteins that are retained in the ER compartment.
Specific secretion bottlenecks of difficult-to-express recombinant proteins.