Ron Do

ASSISTANT PROFESSOR
Genetics and Genomic Sciences
Icahn School of Medicine
United States of America

Professor Genetics
Biography

Dr. Ron Do, Ph.D., is an Assistant Professor in the Department of Genetics and Genomic Sciences. He is appointed as a member of the Charles Bronfman Institute for Personalized Medicine, the Center for Statistical Genetics, the Icahn Institute for Genomics and Multiscale Biology, and the Zena and Michael A. Weiner Cardiovascular Institute. Prior to joining Mount Sinai, Dr. Do was a Postdoctoral Fellow (2010 to 2013) and Instructor in Medicine (2013 to 2015) at the Center for Human Genetic Research at Massachusetts General Hospital and Harvard Medical School, and a research affiliate at the Broad Institute of MIT and Harvard. Dr. Do is a human geneticist interested in understanding the genetic and biological bases of cardiovascular disease. He has pursued this interest by applying methods from human genetics, genetic epidemiology, statistical genetics, population genetics and computing to large-scale human genotyping and sequencing datasets. His research has focused on assessing the role of rare variants on myocardial infarction, inferring causal effects of risk factors for complex disease, and implementing a population genetics framework to measure differences in the efficiency of natural selection between human populations. Multi-Disciplinary Training Area Genetics and Genomic Sciences [GGS] Education BSc, University of British Columbia MSc, University of British Columbia PhD, McGill University Post-doc, Massachusetts General Hospital/Broad Institute/Harvard Medical School Instructor, Harvard Medical School

Research Intrest

Cardiovascular, Computational Biology, Epigenetics, Genetics, Genomics, Human Genetics and Genetic Disorders, Systems Biology

List of Publications
Musunuru K, Pirruccello JP, Do R, Peloso GM, Guiducci C, etal (2010) Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia. The New England journal of medicine Vol: 363.
Do R, Kathiresan S, Abecasis GR (2012) Exome sequencing and complex disease: practical aspects of rare variant association studies. Human molecular genetics Vol: 21.
Do R, Balick D, Li H, Adzhubei I, Sunyaev S, etal (2015) No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans. Nature genetics Vol: 47.
Do R, Stitziel NO, Won HH, Jørgensen AB, Duga S, etal (2015) Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction. Nature 518: 7537.