Biography

The Zhou laboratory is interested in the mechanisms mediating cell-cell communication and their roles in normal development, physiology, and diseases. Specifically the Zhou laboratory is investigating the functions of a large family of tyrosine kinase receptors, the Ephs, and their ligands, the ephrins, in neural circuit formation, eye development, and behavior regulations including motor activity, circadian rhythm, and aggression. The Zhou laboratory employs both in vitro and in vivo techniques, including neuron cultures, transgenic and knockout mice, as well as behavior assays.

Research Intrest

Toxicology

List of Publications
Sheleg, M, Yochum, CL, Richardson, JR, Wagner, GC, Zhou, R. Ephrin-A5 regulates inter-male aggression in mice. Behav. Brain Res. 2015;286 :300-7. doi: 10.1016/j.bbr.2015.03.001. PubMed PMID:25746458 PubMed Central PMC4390541
Biswas, S, Son, A, Yu, Q, Zhou, R, Lo, WK. Breakdown of interlocking domains may contribute to formation of membranous globules and lens opacity in ephrin-A5(-/-) mice. Exp. Eye Res. 2016;145 :130-139. doi: 10.1016/j.exer.2015.11.017. PubMed PMID:26643403 PubMed Central PMC4842153
Buensuceso, AV, Son, AI, Zhou, R, Paquet, M, Withers, BM, Deroo, BJ. Ephrin-A5 Is Required for Optimal Fertility and a Complete Ovulatory Response to Gonadotropins in the Female Mouse. Endocrinology. 2016;157 (2):942-55. doi: 10.1210/en.2015-1216. PubMed PMID:26672804
Das, G, Yu, Q, Hui, R, Reuhl, K, Gale, NW, Zhou, R. EphA5 and EphA6: regulation of neuronal and spine morphology. Cell Biosci. 2016;6 :48. doi: 10.1186/s13578-016-0115-5. PubMed PMID:27489614 PubMed Central PMC4971699
Sheleg, M, Yochum, CL, Richardson, JR, Wagner, GC, Zhou, R. Corrigendum to "Ephrin-A5 regulates inter-male aggression in mice" [Behav. Brain Res. 286 (June) (2015) 300-307]. Behav. Brain Res. 2017; :. doi: 10.1016/j.bbr.2017.08.019. PubMed PMID:28827072