Kelvin Lee

Professor
Department of Immunology
Roswell Park Cancer Institute
United States of America

Professor Oncology
Biography

Kelvin P. Lee, MD, joined the faculty of Roswell Park Cancer Institute in 2006 as Chair of the Department of Immunology and Vice Chair of the Department of Medicine. Dr. Lee is responsible for strengthening existing programs and establishing new clinical and research initiatives and training opportunities and the continued development of scientific and clinically based collaborations to further translational research (“bench to bedside”) programs at RPCI. Dr. Lee came to RPCI from University of Miami Medical School/Sylvester Comprehensive Cancer Center, where he served as Professor of Microbiology and Immunology; Professor of Medicine (Hematology/Oncology); Director of the Cell Banking and Purification Core Facility; Co-Director of the Clinical Oncology Research Program; and Co-Program Leader of the Tumor Immunology Program.Dr. Lee earned his medical degree from University of Michigan (UM) Medical School, Ann Arbor, and completed residency training at the University of Colorado, Denver. Residency training was followed by a clinical fellowship at the UM Medical School and a research fellowship at the UM Howard Hughes Medical Institute. He is a Diplomate of the American Board of Internal Medicine.Dr. Lee is an accomplished national researcher whose investigations on the immunology and biology of multiple myeloma, the second most common blood cancer, are supported by several peer-reviewed grants from the National Cancer Institute and the National Institutes of Health. His cutting-edge research in this area has been presented at professional conferences around the world, including Canada, Greece and Australia. Dr. Lee has authored or co-authored more than 60 journal articles, abstracts and books.

Research Intrest

Novel therapies for multiple myeloma

List of Publications
Rozanski CH, Arens R, Carlson LM, Nair JR, Lee KP, et al. (2011) Long Term Humoral Immunity is Dependent on CD28 Expression in Plasma Cells. J Exp Med 208: 1435-46
Nair JR, Murray ME, Carlson LM, Watkins SK, Lee KP, et al. (2014) Novel Regulation of CD80/CD86-induced Phosphatidylinositol 3-kinase Signaling by Notch1 in IL-6 and Indoleamine 2,3 dioxygenase Production by Dendritic Cells. J Biol Chem 289: 7747-62
Farren MR, Carlson LM, Netherby CS, Lindner I, Lee KP, et al. (2014) Tumor-Induced STAT3 Signaling in Myeloid Cells Impairs Dendritic Cell Generation by Decreasing PKCβII Abundance. Sci Signal 7: 16