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Experts in Anesthesiology
Matthew H Andersen Yaakov Beilin ALEXANDRU I. CARLAN Peter Larsen Daniel S. Talmor Alan Lisbon Sheila M. Ryan-Barnett MICHAEL T. BAILIN JAMES B. KHOURY Peter J. Panzica MARY KRAFT Vimal K. Akhouri Musa Aner Myles D. Boone Ruma R. Bose Somnath Bose Rajiv R. Doshi Matthias Eikermann Stephanie B. Jones Satya Krishna Ramachandran View More
Jaime Garcia-Anoveros

Associate Professor of Anesthesiology, Neurology - Ken and R
Northwestern University Feinberg School of Medicine
United States of America

Professor Anesthesiology
Biography

Our long term line of research involves the identification and characterization of genes required fro the function, formation and degeneration of sensory receptor cells and neurons, and particularly those that mediate nociception and pain. As part of this work, we characterized major pain-transducing ion channels (TRPA1 and the ASICs) as well as genes involves in determining the number of sensory neurons being produced (Insm1). In particular, we found the Insm1 promotes the transition of progenitors in developing neuroepithelia from apical, proliferating and uncommitted (neural stem cells) to basal, terminally-dividing and neuron-producing.

Research Intrest

Cell Biology, Molecular Neuroscience, Neurobiology of Disease, Signal Transduction

List of Publications
Mucolipin Co-deficiency Causes Accelerated Endolysosomal Vacuolation of Enterocytes and Failure-to-Thrive from Birth to Weaning Remis NN, Wiwatpanit T, Castiglioni AJ, Flores EN, Cantú JA, García-Añoveros J PLoS Genetics. 2014 Dec; 10(12): doi:http://dx.doi.org/10.1371/journal.pgen.1004833. PMID: 25521295 PMCID: 25521295 ISSN: 1553-7390
A non-canonical pathway from cochlea to brain signals tissue-damaging noise Flores EN, Duggan A, Madathany T, Hogan AK, Márquez FG, Kumar G, Seal RP, Edwards RH, Liberman MC, García-Añoveros J Current Biology. 2015 Mar 2; 25(5): 606-612. doi:http://dx.doi.org/10.1016/j.cub.2015.01.009. PMID: 25639244 PMCID: 25639244 ISSN: 0960-9822
Insm1 promotes neurogenic proliferation in delaminated otic progenitors Lorenzen SM, Duggan A, Osipovich AB, Magnuson MA, García-Añoveros J Mechanisms of Development. 2015 Nov; 138: 233-245. doi:http://dx.doi.org/10.1016/j.mod.2015.11.001. PMID: 26545349 PMCID: 26545349 ISSN: 0925-4773
Experts in United States of America
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