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Irina Kirpich

Assistant Professor
Department of Medicine
University of Louisville
United States of America

Professor Gastroenterology
Biography

Irina Kirpich is assistant professor at University of Louisville. She received her Bachelor's & Master's degree from Lugansk State University. She earned a Ph.D. from Pomor State University.

Research Intrest

Gut-Liver interactions in alcoholic and nonalcoholic liver disease, Alcohol and dietary fat mediated intestinal and liver injury, Epigenetics and hepatic steatosis,

List of Publications
Y.Wang; Y.Liu; I.Kirpich; Z.Ma; C.Wang; M.Zhang; Jill Suttles; C.McClain, W.Feng Lactobacillus rhamnosus GG reduces hepatic TNF-alpha production and inflammation in chronic alcohol-induced liver injury. Journal of Nutritional Biochemistry, 2013 Apr 22. doi:pii: S0955-2863(13)00039-9. 10.1016/j.jnutbio.2013.02.001. [Epub ahead of print], PMID: 23618528; NIHMS510181
I.Kirpich, W.Feng, Y.Wang, Y.Liu, J.Beier, G.Arteel, K.Falkner, S. Barve, C.J.McClain Ethanol and dietary unsaturated fat (corn oil/linoleic acid enriched) cause intestinal inflammation and impaired intestinal barrier defense in mice chronically fed alcohol. Alcohol, 2013, May;47(3):257-64. PMID: 23453163
I.Kirpich, J.Zhang, L.Gobejishvili, G.Kharebava, D.Barker, S.Ghare, S. Joshi Barve, C.J.McClain, S.Barve Ethanol induced hepatic steatosis involves epigenetic down regulation of CPT1α expression in mice. Alcoholism, Clinical and Experimental Research, 2013, Jul 26. doi: 10.1111/acer.12172. [Epub ahead of print]PMID: 23905631
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