I am an adjunct Associate Professor at National University of Singapore and Duke-NUS Graduate Medical School attached with Depts. of ophthalmology and Neuroscience and Behavioral Disorders (NBD), respectively. I head the Ocular Genetics Group at the Singapore Eye Research Institute and hold the position of a Senior Principal Research Scientist with a concurrent appointment as Director of Laboratory Translational Research. I am a molecular biologist with research focused on understanding the genetic basis of both rare and common eye diseases with Mendelian and/or complex genetic etiology. During my research career that span nearly 20 years I have investigated the genetic basis and biochemical mechanisms of corneal dystrophies, inherited photoreceptor degenerations (IPDs), all forms of glaucoma (POAG, PACG, NTG, congenital glaucoma), as well as quantitative traits of ocular diseases. My research has led to the discovery of genes causative of retinitis pigmentosa, corneal endothelial dystrophies, glaucoma and ocular quantitative traits. I have published more than 89+ peer-reviewed papers, which include articles in Nature Genetics, Molecular Cell, American Journal of Human Genetics and Human Molecular Genetics. Grant funding awarded to me as the principal investigator (PI) has totaled to over S$6 million to date. I have an H index of 30 as well as two patent filings where I have been named a co-inventor.

Genetic basis of both rare and common eye diseases with Mendelian and/or complex genetic etiology, genetic basis and biochemical mechanisms of corneal dystrophies, inherited photoreceptor degenerations (IPDs), all forms of glaucoma (POAG, PACG, NTG, congenital glaucoma), quantitative traits of ocular diseases.