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Experts in Microbiology
Krishna Sundari Kenneth C. Carroll Roy D. Welch Ratan Gachhui Lacy Daniels Hardik Pathak Varsha Gupta Smriti Gaur Alok Kalra Franklin, Portugal Mohammad Hayatul Islam Professor Clive Ronson Anthony Garza Joseph Ashour Evelyn de Souza Oliveira Lopes Alexander Borisovich Prikhodko Prof. M.S. Dkhar Prof. H. Kayang Rizwana Rahim Dr. Papiya Ramanujam View MoreCAROL DUFFY
biological sciences
University of Alabama
United States of America
Ph.D., Microbiology, University of Iowa, 2000 Postdoctoral research: Cornell University
My research interests lie in elucidating the mechanisms used by herpes simplex virus type 1 (HSV-1) to replicate within its host. The herpesviruses have been co-evolving with their hosts for millions of years, and have consequently developed elaborate mechanisms for replication and evasion of their hosts’ defense systems. HSV-1 is a neurotropic herpesvirus that infects ~80% of young adults worldwide. Infection of its human host is initiated with a lytic infection of the mucosal epithelium and continues through invasion of the peripheral nervous system that usually leads to establishment of a reactivatable latent infection. On occasion, HSV-1 spreads to the central nervous system, causing the most common type of sporadic viral encephalitis seen in western countries. In addition, HSV-1 can infect the corneal epithelium, causing a disease known as herpes simplex keratitis that often results in vision damage.