Brahm Segal

Professor
Department of Immunology
Roswell Park Cancer Institute
United States of America

Professor Oncology
Biography

Prior to joining RPCI, Dr. Segal completed a fellowship in Infectious Diseases at the National Institute of Allergy and Infectious Disease, NIH, Bethesda, MD. He joined the staff of RPCI in 1999, as Consultant, Division of Infectious Disease, Department of Medicine, and was appointed Chief of the Division in 2000.He is currently Professor of Medicine, Vice Chair of Faculty Development in the Department of Medicine at the University at Buffalo School of Medicine & Biomedical Sciences and Professor of Oncology and Member, Dept. of Immunology at RPCI. Dr. Segal has authored or co-authored more than 100 peer-reviewed publications as well as numerous book chapters.

Research Intrest

NADPH oxidase as a critical regulator of host defense, inflammation, and injury, Innate immune responses in the tumor microenvironment, Development of novel immune-based prognostic biomarkers and therapeutic targets for cancer

List of Publications
Zucker SN, Fink EE, Bagati A, Mannava S, Segal BH, et al. (2014) Nrf2 amplifies oxidative stress via induction of Klf9. Mol Cell 53: 916-28
Pomakova D, Segal BH, (2014) Prevention of infection in cancer patients. Cancer Treat Res 161: 485-511
Tam JM, Mansour MK, Khan NS, Seward M, Segal BH, et al. (2014) Dectin-1 dependent LC3 recruitment to phagosomes enhances fungicidal activity in macrophages. J Infect Dis pii: jiu290