Prof. John A. Rudd began working on the mechanisms of emesis control as part of PhD studies in 1988. Research investigated emetic responses resistant to 5-HT3 receptor antagonists, the discovery of broad inhibitory anti-emetic drugs, and the mechanism of anti-emetic action of dexamethasone. Prof. Rudd subsequently developed the ferret model of cisplatin-induced acute and delayed emesis and revealed the potential of NK1 receptor antagonists to reduce delayed emesis. He is currently at the Chinese University of Hong Kong and has an Emesis Research Group that has strong links with the international pharmaceutical industry. Prof. John A. Rudd began working on the mechanisms of emesis control as part of PhD studies in 1988. Research investigated emetic responses resistant to 5-HT3 receptor antagonists, the discovery of broad inhibitory anti-emetic drugs, and the mechanism of anti-emetic action of dexamethasone. Prof. Rudd subsequently developed the ferret model of cisplatin-induced acute and delayed emesis and revealed the potential of NK1 receptor antagonists to reduce delayed emesis. He is currently at the Chinese University of Hong Kong and has an Emesis Research Group that has strong links with the international pharmaceutical industry.

Gastroenterology