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Tim F. Greten, M.D.

Head, Gastrointestinal Malignancy Section
Thoracic and Gastrointestinal Oncology Branch
Centre of Hepatology, Gastroenterology and Dietetics
Germany

Business Expert Gastroenterology
Biography

 Dr. Greten is an expert in GI Oncology and tumor immunology. His specific research focus is liver cancer and immunology. He is trying to better understand how tumors in the liver interact with the immune system. Dr. Greten has his received his training in Medical Oncology, Gastroenterology and Hepatology in Germany and has been performing basic and translational research studies in tumor immunology for more than 20 years. He is currently studying novel immune based approaches to treat patients with primary hepatobiliary tumors and patients with tumors of the GI tract metastasizing into the liver.

Research Intrest

 ) Gastrointestinal Cancer 2) Tumor immunology and Immunotherapy 3) Hepatocellular Carcinoma 4) Liver Immunology and Cancer 5) Preclinical and Translational Studies

List of Publications
Tremelimumab in Combination with Ablation in Patients with Advanced Hepatocellular Carcinoma. Duffy AG, Ulahannan SV, Makorova-Rusher O, Rahma O, Wedemeyer H, Pratt D, Davis JL, Hughes MS, Heller T, ElGindi M, Uppala A, Korangy F, Kleiner DE, Figg WD, Venzon D, Steinberg SM, Venkatesan AM, Krishnasamy V, Abi-Jaoudeh N, Levy E, Wood BJ, Greten TF. Journal of Hepatology. 2016. [ Journal Article ] A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells. Hoechst B, Ormandy LA, Ballmaier M, Lehner F, Krüger C, Manns MP, Greten TF, Korangy F. Gastroenterology. 135: 234-43, 2008. [ Journal Article ] Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma. Kapanadze T, Gamrekelashvili J, Ma C, Chan C, Zhao F, Hewitt S, Zender L, Kapoor V, Felsher DW, Manns MP, Korangy F, Greten TF. J. Hepatol. 59: 1007-13, 2013. [ Journal Article ]
NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis. Ma C, Kesarwala AH, Eggert T, Medina-Echeverz J, Kleiner DE, Jin P, Stroncek DF, Terabe M, Kapoor V, ElGindi M, Han M, Thornton AM, Zhang H, Egger M, Luo J, Felsher DW, McVicar DW, Weber A, Heikenwalder M, Greten TF. Nature. 531: 253-7, 2016. [ Journal Article ] Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression.. Eggert T, Wolter K, Ji J, Ma C, Yevsa T, Klotz S, Medina-Echeverz J, Longerich T, Forgues M, Reisinger F, Heikenwalder M, Wang XW, Zender L, Greten TF. Cancer Cell. 30: 533-47, 2016. [ Journal Article ]
Experts in Germany
Dr. Reinhard Achenbach Dr. Rainer Albertz Patrick Bahl Dr. Theol Dieter Baltzer Ellen Beinert Dr. H.C. Micheal Beintker Leonardo Bandarra Sonja Bartsch Matthias Basedau ALEXANDER DÖLECKE Joachim Betz Maria Bondes Elisabeth Bunselmeyer Alexandr Burilkov Alexander De Juan Sandra Destradi Yazan Doughan Dr. Albrecht Beutel Dr. Yauheniya Danilovich Dr. J. Cornelis De Vos Alexander Dolecke Larissa Figgen Dr. Niclas Forster Steffen Gotze Dr. Christian Grethlein View More