Ludwig Cancer Research is a global community of leading scientists pursuing innovative ways to prevent and control cancer. From basic research to clinical trials, in individual laboratories or as part of international teams, our researchers are tackling the hardest questions, spotting the connections and the possibilities. At Ludwig, we test our work against the one measure that matters — improving human health. Ludwig Cancer Research is a global community of leading scientists pursuing innovative ways to prevent and control cancer. From basic research to clinical trials, in individual laboratories or as part of international teams, our researchers are tackling the hardest questions, spotting the connections and the possibilities. At Ludwig, we test our work against the one measure that matters — improving human health.

I was initially trained as a medical doctor, worked briefly in pediatric oncology and pediatric AIDS, then switched to basic research after obtaining my PhD. My research is focused on understanding the structure and function of cytokine receptors and their associated proteins, JAKs (Janus kinases) in physiologic and pathologic blood formation. We aim to elucidate the molecular bases of blood cancers, especially chronic myeloproliferative neoplasms (MPNs) such as Polycythemia Vera, Essential Thrombocythemia and Myelofibrosis, as well as secondary acute myeloid leukemia that derive from their progression. In addition to being a member of the Ludwig Institute, I am a Professor and Head of Cell Signaling Pole at the Université catholique de Louvain's de Duve Institute. I am teaching advanced molecular biology to biomedical students and cell biology to medical students, and I am serving on review panels such as the European Research Council's panels for advanced grants.