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Experts in Veterinary Sciences
Gregory M. Andraso Dr. Zoltán Zomborszky Dr. Gábor Tornyos S.P Tiwari Nitin Dade Dr. Roland Pósa M.K.Gendley Meenu Dubey Raina Doneria Mohan Singh K.Mukhejee Asit Jain Rajesh Yadav Mona Arora R.Mathivanan Luca Aresu Deepti Kiran Bara Kaiser Parveen O.P Mishra J.R.Khan View MoreYAMATE Jyoji
Professor
Veterinary science
Osaka Prefecture University
Japan
College of Life, Environment, and Advanced Sciences , Graduate School of Life and Environmental Sciences, School of Life and Environmental Sciences
By establishing rat transplantable tumor lines and cultured cell lines, the characteristics of neoplastic cells and pathobiological nature of the original cells have been investigated histopathlogically, immunohistochemically and molecular pathologically, and the mesenchymal differentiation and relevant growth factors have been clarified using the mesenchymal tumor lines established as pluripotential stem cells. Additionally, by establishing rat models of chemically-induced hepatic and renal fibrosis, the complicated pathogenesis of intractable diseases has been investigated with regards to heterogeneous functions of myofibroblasts and macrophages. These animal models contribute to studies on biomedical sciences, and become useful tools for evaluation system of medical drug development.