Associate Professor
Department of Immunology
Ross University School of Veterinary Medicine
United States of America
Joseph Lau, PhD was working as Distinguished Member in the Department of Molecular and Cellular Biology at Roswell Park Cancer Institute. The central thrusts of the research program are: 1) to elucidate the functional contribution of sialic acid epitopes in normal and malignant processes, and 2) to elucidate the molecular pathways that regulate the attachment of sialic acids. The current main, on-going project is to examine the contribution of the sialyltransferase ST6Gal-I in innate immune responses such as inflammation. There are a number of corollary projects: a) to examine the interaction between sialyltransferases and how this interaction influences the final outcome of sialyl-glycan structures; b) to assess the biologic role of sialyl epitopes and cognate sialyltransferases in development of immune functions; c) To assess the influence of sialic acids on tumor cell surfaces in anti-tumor immunity.
to examine the contribution of the sialyltransferase ST6Gal-I in innate immune responses such as inflammation.