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Jairaj K. Acharya Thomas P. Fondy Swarnali Acharyya Bachir Alobeid Richard Baer Aneel K Aggarwal Margaret H Baron Benjamin O. Anderson Parveen Bhatti Marita Zoma Chu Chen Eric Chow Giuseppina Carbone Asma Amleh Katia Basso Govind Bhagat Shiuan Chen Casey L. Daniel WenYong Chen Natalie R. Gassman View More
Hana Janouskova

Research scientist
Research scientist
Oncology Institute of Southern Switzerland
Switzerland

Academician Oncology
Biography

post-Doctoral from Oncology Research (IOR), Bellinzona-Switzerland. PhD from University of Strasbourg,France.

Research Intrest

Molecular Biology, Cancer Biology, Targeted Therapy, Bromodomain proteins, Protein Degradation, Endometrial cancer, Glioblastoma pathology, Prostate cancer, p53 Pathway and working on a paradoxical paradigm in oncogenomics, whereby mutations within the same domain of a particular gene evoke opposing drug susceptibilities

List of Publications
Janouskova H, Maglott A, Leger DY, Bossert C, Noulet F, Guérin E, Guenot D, Pinel S, Chastagner P, Plénat F, Entz-Werlé N. Is nutlin-3A a new therapeutic option for a subset of high grade glioma expressing a wild type P53 and high α5β1 integrin?. In2ème Colloque Inter-régional Grand-Est de Recherche Translationnelle en Oncologie, ONCOTRANS 2011 2011 Sep 8.
Janouskova H, Ray AM, Noulet F, Lelong-Rebel I, Choulier L, Schaffner F, Lehmann M, Martin S, Teisinger J, Dontenwill M. Activation of p53 pathway by Nutlin-3a inhibits the expression of the therapeutic target α5 integrin in colon cancer cells. Cancer letters. 2013 Aug 19;336(2):307-18.
Janouskova H, Maglott A, Leger DY, Bossert C, Noulet F, Guerin E, Guenot D, Pinel S, Chastagner P, Plenat F, Entz-Werle N. Integrin α5β1 plays a critical role in resistance to temozolomide by interfering with the p53 pathway in high-grade glioma. Cancer research. 2012 Jul 15;72(14):3463-70.
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