Macroalgae is a collective term used for seaweeds and other benthic (attached to the bottom) marine algae that are generally visible to the naked eye. Larger macroalgae are also referred to as seaweeds, although they are not really “weeds”. Marine macroalgae (seaweeds) have been traditionally used by coastal populations for food, feed, disease remedy, and organic fertilizer since ancient times. There is evidence that species in Ochrophyta, Rhodophyta, and Chlorophyta Phyla have been used for food and medicine in south Chile about 13,000 years ago. Likewise, they have been used for food in China, Japan, Korea, Indonesia, Malaysia, and other countries that have exported the practice of using macroalgae as a food to other parts of the world. Traditional practice has been based on harvesting macroalgae directly from the sea. However, in the last 50 years methodologies for macroalgae cultivation have been developed, boosting macroalgae cultures, whether there are sea-based cultures or cultures in seawater ponds. Due to that, the production of macroalgae has increased dramatically in the last two decades. World production rose from 10.51 Mt in 2000 to 30.45 t in 2015; macroalgae cultivation represented over 95% of algae production.